The chemical name of tenofovir disoproxil fumarate is 9-[( R )-2
HEPATIC FUNCTION SHOULD BE MONITORED CLOSELY WITH BOTH CLINICAL AND LABORATORY FOLLOW-UP FOR AT LEAST SEVERAL MONTHS IN PATIENTS WHO DISCONTINUE TRUVADA AND ARE CO-INFECTED WITH HIV AND HBV.
Genotypic analysis of these isolates identified the M184I/V and/or K65R amino acid substitutions in the viral RT.
Emtricitabine: Emtricitabine-resistant isolates of HIV have been selected in vitro.
Emtricitabine: The in vitro antiviral activity of emtricita-bine against laboratory and clinical isolates of HIV was assessed in lymphoblastoid cell lines, the MAGI-CCR5 cell line, and peripheral blood mononuclear cells.
The IC values for emtricitabine were in the range of 0.0013-0.64 µM (0.0003-0.158 µg/m L).